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Overview of AQUAFLOR® 50% Premix*


AQUAFLOR is also marketed as AQUAFEN®, FLOROCOL® and NUFLOR® in some markets. Check with your Merck/MSD Animal Health representative regarding the products and indications available for your area.

AQUAFLOR® 50% Premix is a synthetic, broad-spectrum, bactericidal antibiotic indicated for the treatment of diseases of fish caused by bacteria susceptible to florfenicol.

AQUAFLOR inhibits bacterial protein synthesis, and is active against a number of bacterial pathogens in fish includingAeromonas salmonicida, Vibrio salmonicida,Vibrio anguillarum, Yersinia ruckeri, Edwardsiella ictaluri, Edwardsiella tarda, Streptococcusspp.,Flavobacterium columnare, Flavobacterium psychrophilum, Renibacterium salmoninarum, Piscirickettsia salmonis and Photobacterium damselae subsp.piscicida.


  • Can be fed from fingerlings to food fish

  • May be used in sinking or floating feeds

  • Stable under high-temperature extrusion processes

  • Short withdrawal time

  • Dependable

    • Broad-spectrum antibiotic with unique molecular structure

    • Proprietary formulation developed specifically for aquaculture

    • Keeps fish healthy, so they stay on feed for optimum survival, growth and returns

    • Reduces mortality so you can produce more fish


  • Studies show that fish readily consume feed with Aquaflor — palatability comparable to unmedicated feed

  • Minimize wasted feed, maximize antibiotic uptake

  • Uniform granulation for optimum distribution in feed and more accurate dosage delivery


  • No adverse effects on fish behavior or performance, even when tested at 5X and 10X dose rates

  • Developed specifically for fish and food-animal species — not used in human medicine

  • Friendly to environment — no significant risk to aquatic ecosystems

*Aquafen 2.5% Premix is available in Japan for the treatment of diseases of fish caused by bacteria susceptible to florfenicol.

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